Methylcobalamin B12 is
The Only Vitamin B12 to Take

When talking about the treatment of vitamin B12 deficiency, Methylcobalamin B12 is one of the best forms of Vitamin B12  for the job- despite that your doctor will almost certainly give you inferior forms. 

Vitamin B12 is really the general name given to a class of compounds more scientifically called the Cobalamins, and rightly so since all of these compounds end in -Cobalamin, In fact, doctors and scientists call Vitamin B12 Deficiency ‘Cobalamin Deficiency’. While there are many ‘cobalamins’, only 3 are generally used as dietary supplements, namely:

  • Hydroxycobalamin B12
  • Cyanocobalamin B12
  • Methylcobalamin B12



While all 3 are called ‘Vitamin B12’, they are not all the same, and Methylcobalamin B12, even though it is technically considered a 'Coenzyme' of vitamin B12, is clearly the superior form and is really the best form that should ever be considered for vitamin B12 deficiency treatment.

Although Methylcobalamin B12, also called Mecobalamin and Methyl B12, is the preferred form, most doctors in the US are not educated about the benefits of Methyl B12 therapy, and another form called Cyanocobalamin is the most commonly used in the medical world and is often given as ‘B12 Shots’ in the office for those with certain medical conditions. But cyanocobalamin is actually the worst choice of the 3, even though it is the most widely used.

8 Reasons to Love Methylcobalamin B12

Not only does cyanocobalamin require a higher dosage for the same effectiveness, but the Facts about Vitamin B12 show that it absolutely does not work for many problems requiring Vitamin B12 Deficiency Treatment. Because it is inferior to other forms, it has been repeatedly suggested by several researchers that it be completely removed from the market!

While Japan and Great Britain exclusively use Methyl B12 in their prescription formulations, and have removed Cyanocobalamin, US doctors still wrote over 1 1/2 MILLION prescriptions for Cynocobalamin in 2008 alone! So much for the 'evidence based medicine' that doctors claim to use.


“Clinical trials have repeatedly shown
superior results using methylcobalamin”

Rob Faigin
author Natural Hormonal Enhancement

Why methyl b12 is almost never used by doctors is baffling. Not only is it effective but it is inexpensive and available in both sublingual preparations and injectable form. This ignorance has only hurt the many people that could very well benefit from the Sublingual Methylcobalamin Supplements that would not benefit from the other forms.

What is Methylcobalamin B12 Used For

While Methyl B12 can be used in all situations that call for vitamin B12, it is absolutely the only form that should be used for those with the MTHFR Gene Mutation, and with Mental Changes from B12 Deficiency -including those from Dental Nitrous Oxide and Nipride - which deplete vitamin B12 levels.



While using Methyl b12 is still controversial in some of these conditions, there have absolutely been studies and anecdotal evidence that very high doses have been used to improve and even REVERSE conditions like:

  • Alzheimer's Disease
  • Autism
  • Multiple Sclerosis
  • Bell's Palsy
  • Dementia
  • ALS
  • Subacute Combined Degeneration

and that these conditions, in some cases, might actually be undiagnosed Vitamin B12 Deficiency Symptoms and/or symptoms of Aspartame Side Effects- which is detoxified by Methylcobalamin B12- in many, many cases!

Alzheimer’s disease is a particularly tragic example of the unwillingness of US doctors to use this vitamin therapy in practice. Several studies have shown dramatic reversal of Alzheimer’s symptoms in a certain percentage of people with the disease, yet most doctors would adamantly refuse to even attempt mecobalamin therapy for this purpose.


“Methylcobalamin is the form found in food
and has much higher bioavailability than
the form most widely available 
in supplements, cyanocobalamin”

B12 (Cobalamin)

Methyl B12 For Detoxification

One of the main ways that methyl B12 works, is through the detoxification of toxic substances in the body. A process called ‘Methylation’ is a critical component of the detoxification process and Methylcobalamin is actually able to replenish the ‘methyl’ portion of the chemical reaction required for methylation. Methylcobalamin is a critical supplement for those with MTHFR Gene Mutations, which makes them unable to detoxify well.

Methylcobalamin B12 has been shown to be effective in helping the body to get rid of different kinds of toxins including:

  • Mercury
  • Arsenic
  • Mycotoxins from mold
  • Glutamine (like from MSG and Aspartame)

But the other forms of Vitamin B12 actually require this methyl donor in order to convert into the active form of Methycobalamin B12 in the blood; therefore, people who already have methylation detoxification problems from MTHFR Gene Mutations or other reasons, like children with autism, or those who have liver problems can actually be made worse if other forms of vitamin B12 are administered!



So, if you need vitamin B12 deficiency treatment, it's likely that your doctor is going to prescribe you the WRONG kind of Vitamin B12. When your doctor hands you a prescription or recommends an over the counter formula, make sure that you are ONLY taking Sublingual Methylcobalamin B12. If your doctor tells you that you need to have Vitamin B12 shots, be sure to read about Vitamin B12 Shot Problems and politely decline his shots and simply buy some Methylcobalamin B12 Supplements for your Vitamin B12 Deficiency Treatment or your fatigue or neurologic issues instead- you'll be glad that you did!

Vitamin B12 Deficiency Treatment

Vitamin B12 Resources

Already Answered Questions about Vitamin B12

Click below to see already answered questions about Vitamin B12?

Severe B12 deficiency, methylcobalim made it worse 
Hi, I have severe deficiency, my symptoms are severe mental disturbances , memory issues, my hands, feet feel numb. I tried taking methycobalim supplements …

Sever fatigue AFTER taking methylcobalamin 
Despite my serum b vitamines being at the high end of normale range I decided to trial methlcobalamin. My symptoms are a sore and sensitive tongue, …

B12 supplements 
My B12 level was 134pg/ml before a month.I have taken 4 injections on alternate day of 2500mcg. After that I have taken weekly 6 injections of 500mcg plus …

Methyl-B12 chelates Arsenic and Mycotoxins? 
Do you have some research citations I can show to my doctor to confirm that methyl-B12 will help detoxify or chelate arsenic and also mold mycotoxins? …

Methyl B-12 2500 mcg 
Ok... I have purchased GNC Product, Methyl B-12 2500 mcg. I am 48 years old and wife is 46 years old. We have started feeling the pulls of the age …

Pills or injections 
E-mail I would like to know if Methyl B12 pills are just as good as Methyl B12 injections. Thank you. Linda Simpson

Am I Taking Too Much Vitamin B12? 
Can you take too much B12 and can it be harmful? I came to your site from The Tendon Expert site (Joshua)and am at present following his steps to heal …

Adensosylcobalamin vs other forms of Vitamin B12 
I've read that adenosylcobalamin is another "active" form of B12 that is supposedly the most easily absorbed form of B12. What is your opinion? Thanks. …

How much B12 to take? 
I've just been diagnosed with mild peripheral neuropathy and my only symptoms are numbness in the balls of my feet and toes with a smal amount of tingling …

which food would give you the correct type of B12 
which food would give you the correct type of B12, wouldn't it be better to try to get this B12 from your natural diet if you can?

How many tabs should I take per day? I suffer from SAD and believe although my Dr. says my b12 is fine that I'm lacking after reading the above. I have …

Methyl B12 and eye disorder 
I seem to have read somewhere that Methyl B12 is the only effective form of B12 for some kind of eye disorder, but I don't remember the name of the disorder. …

Methlycobalamin and prostate cancer 
I really appreciate your website! It's so informative. I was wondering if it would be ok for someone with high PSA count to take MB12? If it is ok, Then …

B-12 Controversy 
A leading biochemist with a vitamin company who healed himself of serious illness says that the Methyl B12, while much better than the cyano B12, only …

I've just found your site and thank God for it. I been on Dr. John Dommisse site but can't afford his fees and since looking at your site I think what …

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