Comments for Severe Fatigue after Taking Vitamin D

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Lots of thoughts on this...
by: Kerri Knox, RN- The Immune Queen!

Hi Tina,

So, the first thing that you should check is if your doctor ordered the Vitamin D to be taken one pill every DAY for 12 days or once per WEEK for 12 weeks.

Generally, they order Vitamin D once per week and not once per day. But don't worry, even if you made a mistake, it really doesn't make any difference because many doctors give 600,000 IU's all at once for Vitamin D Deficiency Treatment.

So, the first problem here is not that you took too much, but that you are taking Prescription Vitamin D in the first place, which researchers do not recommend.

Instead, they recommend that people take Vitamin D3 Supplements instead.

So, the first thing that you could do is to change supplements. The second thing that you could do is to take your dose just before you go to bed when you don't have to do anything important for a few days. Then if you are tired, just get some sleep.

Also, if you are a night owl, you are DEFINITELY negatively affecting your adrenal glands which is likely contributing to Adrenal Gland Fatigue. And since the adrenal glands require magnesium to function well- and it USES UP magnesium in order to create the active form of Vitamin D in your blood, its possible that you are becoming magnesium deficient due to taking the Vitamin D.

And when you are magnesium deficient, your adrenal glands suffer and make you tired.

So, you could also take magnesium supplements using the Magnesium Dosage page as a guideline to see if that helps.

By the way, you mentioned that you don't like to take medication. Vitamin D is NOT a medication!!! It is a NUTRIENT that your body NEEDS and that you have not been getting sufficient amounts of!!

Please, never think of nutrients as drugs. There is never a drug that your body is deficient in, but there are plenty of nutrients that you require to survive. And YOU need Vitamin D- for the rest of your life, and you MUST get it somewhere. So, for the rest of your life, you need to either get enough sun or supplements to meet your needs.

Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
Easy Immune

High Anxiety and Vitamin D
by: Jimmy

I was recently diagnosed with an extremely low level of Vitamin D ( I have 4 out of the 40 or 50 that I need according to my doc - whatever that means). I was presrcribed 50,000 units of Vitamin D (ergocalciferol) and I am terrified to take it.

I have an anxiety problem and the slightest change in my body sends me into very scary panic attacks. I am scared that the Vitamin D pills will do what some others are writing about as far as bone/muscle pain or upset stomach/nausea.

I saw where you said people should take a supplement, not a pill to avoid the stomach problems. But what about the bone/muscle pain or tingling in the extremities? I am not much for toughing it out with change in my body at all though.

What should I do?

You probably have severe magnesium deficiency...
by: Kerri Knox, RN- The Immune Queen!

Hi Jimmy,

With your extremely high anxiety and nervousness, it's almost a sure thing that these are severe Signs of Vitamin D Deficiency.

So, read the Magnesium Dosage page and for the next week, get your cells saturated with magnesium. Once you have accomplished this, it's very likely that you will feel much calmer and have less anxiety. After a week, start taking Vitamin D3 Supplements at the same dosage instead of the Prescription Vitamin D that your doctor prescribed.

While you may be afraid of the Side Effects of Vitamin D, you also need to think logically and be even MORE afraid of the long term consequences of having your vitamin d level at a 4 !! Realize that many of your CURRENT problems are very likely the RESULT of that low vitamin d level and the choices that you have made in your life that have contributed to the low vitamin d level.

So, get your magnesium level up and your ability to withstand stress will likely be improved, then make the decision whether you are willing to risk short-term discomfort for the long-term benefits- or not! It's up to you and it's a decision that you need to make.

But if you continue to take the vitamin d at the dosage recommended (please don't take lower dosages as it will NOT help decrease the side effects and will only make them last longer), then the side effects will eventually pass and it is likely that you will feel better than you have in years.

It's also possible that you will experience ZERO side effects and you will feel better immediately. I have had clients and people on this board feel better than they have in years after the first dose. In fact, the people who experience side effects from vitamin d are in the extreme minority.

If you read the Side Effects of Vitamin D page, you'll see that in hundreds of research studies, there were ZERO side effects- and I believe that the vast majority of side effects experienced by people are from:

Magnesium Deficiency


Poor quality supplements

Eliminate those two possibilities and you'll eliminate the possibility of many problems. Also, when you take your vitamin d, please go out and DO SOMETHING!!! I see so many people take their pills and then sit there waiting to see what will happen. Do something active and engaging so that you don't notice every sensation in your body after you take your supplement!

Vitamin D and Magnesium Supplementation
by: Elias

I was found deficient in Vitamin D, 15 ng/dl and I started supplementing with Vitamin D3 7500 IU per day. In the beginning I was realy astonished by the side effects and I read in your site about the Magnesium involvement in the process of Vitamin D supplementation.

I started supplementing Magnesium 750 mg per day.

I have read in the University of Maryland Medical center that during Magnesium supplementation in order a lot of it to be absorbed by the cells and not to stay in the colon and create loos stools one needs to take high doses of Vitamin B6.

I have tried it WITH 50 TO 100 mg OF B6 per day and so far works.


Magnesium and b6
by: Kerri Knox, RN- The Immune Queen!

Hi Elias,

Thanks for that. I would love to see that study if you have the URL. That would be great.

Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
Immune System

B6 and Magnesium
by: Elias

Hi Keri

The URL of Maryland Medical Center is :

Bottom of page:
"How to Take It:

Be sure to check with your health care provider before taking magnesium supplements and before considering them for a child. Under certain circumstances, such as certain heart arrhythmias or preeclampsia, a doctor will give magnesium intravenously (IV) in the hospital.

It is a good idea to take a B vitamin complex, or a multivitamin containing B vitamins, because the level of vitamin B6 in the body determines how much magnesium will be absorbed into the cells.

Dosages are based on the dietary reference intakes (DRIs) issued from the Food and Nutrition Board of the United States Government's Office of Dietary Supplements, part of the National Institutes of Health."

Thanks for that ....
by: Kerri Knox, RN- The Immune Queen!

Thank you, thank you. Unfortunately, they don't give any resources for their information so I can't back that information up with any studies.

I looked around after you mentioned it and couldn't find any actual research on that- although there are many conditions that practitioners will give 'Magnesium and B6' for, so it's likely to be true.

I just like to have research to back everything up. If you run across one, I'd love it if you let me know.

Thanks so much for getting that information to me. It is much appreciated.

Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
Immune System


PS: If you found this website helpful, please consider using the
Easy Immune Health Product Store the next time you purchase your supplements online. Thank you for visiting my site!

Upon further investigation...
by: Kerri Knox, RN- The Immune Queen!

Upon further research I found a study SPECIFICALLY designed to test this theory and found that it's NOT true that B6 increases magnesium absorption except at high doses that could cause problems (It's not advisable to take b6 in doses higher than 600 mg per day) and the study required up to 1.5 GRAMS in order to get increased intestinal absorption of magnesium.

Here's the study Vitamin B6 and Magnesium.

Well. And I found one that showed that it DID help.

Effect of vitamin B-6 on plasma and red blood cell magnesium levels in premenopausal women- interestingly, in this study the women were specifically chosen because they had low magnesium levels. So, it's possible that B6 only helps increase absorption in those that are truly deficient.

So, it certainly doesn't seem like there is a LOT of evidence to make a claim that it increases magnesium absorption. But there's absolutely no harm and certainly a lot of OTHER good reasons to be taking B6 so that I will definitely be recommending that as a possible way to absorb more magnesium.

And if it turns out that it really does help magnesium absorption, then this is also another reason why I urge people to not JUST take vitamin d or JUST take magnesium, but to take a high quality multivitamin supplement like Beyond any Multiple.

People have a VERY hard time believing that they could POSSIBLY be just vitamin d deficient, but there is almost no one who is deficient in JUST one nutrient- and it's smart to cover all of the bases.

Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
Immune System


PS: If you found this website helpful, please consider using the
Easy Immune Health Product Store the next time you purchase your supplements online. Thank you for visiting my site!

Vitamin D3...not D2
by: Anonymous

It's my understanding that vitamin D2 (ergocalciferol, mentioned above) may be harmful, and that D3 is the form that should be supplemented.

Could you discuss this?

I've discussed it several times...
by: Kerri Knox, RN- The Immune Queen!

I've actually done several pages on this topic. You can take a look at my pages on:

Prescription Vitamin D


Vitamin D3

and that should answer your questions.

I don't know that I would call D2 'harmful', although there seems to be a slightly higher risk of toxicity with d2, but I would call it 'inferior' more than 'harmful'. Also, the fact that it may not even act on the genes that contribute to the benefits that you would want to take vitamin d for in the first place makes me want to call it more 'inferior' for this reason as well. But I think that calling it harmful is not very accurate. And if someone could only choose between no vitamin d and taking d2, I would encourage them to take the D2 over taking no vitamin d.

Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
Immune System


PS: If you found this website helpful, please consider using the
Easy Immune Health Product Store the next time you purchase your supplements online. Your support allows me to keep this site running and educating as many people as possible. Thank you!

Vitamin D3 was below 4
by: Anonymous

Hello , few years back in 2013 i was diagnosed with bone tb , doc did an x-ray and vit D3 test, x-ray showed that i have tb and my vit D3 was below 4. I was treated for tuberculosis but they didn't test my vit d3 again. Now i am married and my son is 8 months old, i was feeling tired, insomnia , weak bones. I went to same doctor he said my vit d3 is low. He gave me D max vit d3 2000 IU to take daily. After starting this i have weak knee, tired and sleepy . I should be feeling energetic but some how my muscles ache .

Severe anxiety
by: Carolina

I went on diet couple months ago and I knew I was loosing weight however my body started developing absecess from no where and I ended up having a bag of abscess in the rectum area . Anyway I went hospital and I didn’t do surgery and I took high level of antibiotics, prednisone and the anxiety started every day more and more .. I didn’t know why I feel these thoughts and why .. I left the hospital and my anxiety severe everyday .. anyways I stayed 4 months and the same bag came back full of abscess and again hospital antibiotics, etc.. went out with severe anxiety .. and after 2 moth again the bag came back this time I agreed for surgery to open the abscess and drain it .. anyway upon accepting the surgery doctors insist me take Iron I had anemia .. and since then I took iron pills twice a day and my anxiety lowered a lot but I do still have some panic attacks but wayyy better than before .. last 2 month I did blood test and my anemia was still low 24 but not as before where it was 9 .. any way my Vjtamin D was 26L dr told me it’s low by when I started taking 2000 D3 IU I felt anxious and weird so I stopped but I need to take vitamin D because I’m low but every time I try taking vitamin D , magnesium or vitamin c I feel crazy a lot of anxiety I don’t know what to do.. I know my anemi still kinda low but other vitamins make me anxious a lot .. thank you for ur help hopefully I get some helpful tips

by: Ted

I was told by my doctor to take vitamin d3 after taking them I began to feel very tired thought it was just me but after taking again I was overcome with extrem fatigue so I stopped again and my tiredness went

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