Low testosterone levels, low body temp, cold intolerance, infertility

by Anthony
(Denmark)

I've read almost all the information available on your site and really appreciate all the insightful information you provide!


I'm a 26 year old male who has had a problem with low testosterone levels since I was 19. I also seem to have hypothyroid symptoms (low body temp, cold intolerance, fatigue) and low fertility (see test results below). I've been to various doctors and the diagnoses have ranged from hypochondriac to hypothyroidism so I don't really know what to make of it all. I've been offered thyroid meds but I want to find the root cause before going on any medication.

My half-brother has Celiac disease but my blood test for celiac (while eating gluten) came back negative. However, I have gone on a gluten-free diet recently after reading you articles on gluten sensitivity. I'm obviously hoping that non-celiac gluten sensitivity is the root cause of all of my issues but I'm finding it hard to believe because I don't see any indications of malabsorption on my blood tests. From what I understand, in order for gluten to be a problem and cause hormonal imbalances - malabsoroption must be present, right?

I will obviously stay on the gluten-free diet for a couple of months and see if I improve. If
I don't, do you have any other ideas on what might be wrong? Doctors can't explain it and don't want to investigate further due to financial constraints and I'm completely out of ideas. I've had a brain MRI, chest X-ray and abdomen ultrasound and everything came back fine, testes are working fine as well, no thyroid antibodies, no diabetes. I've posted the results from my latest blood test below (taken at 8 AM). If you've got time to take a look at my case, I would be incredibly grateful. Thank you!

TSH: 2.82 mU/L (0.2-4.00) (has risen from ~1.5 since I started taking 50 mg of Lugol's per day)
Hemoglobin: 141 g/L (134-170) (my level has always been around 138-141)
Erythrocyte Particle Concentration: 4.4 (4.2-5.7)
Hematocrit: 0.42 (0.39-0.50)
MCV: 94 fL (82-98)
MCH: 32 pg (27-33)
MCHC: 338 g/L (317-357)
Leukocyte Particle Concentration: 4.1 (3.5-8.8)
Thrombocyte count: 141 (145-348) (low - is this a problem?)

Sodium: 142 mmol/L (137-145)
Potassium: 4.2 mmol/L (3.6-5.0)
Calcium: 2.51 mmol/L (2.15-2.50) (has risen from ~2.3 since getting vit D levels into the optimum range)
Albumin: 42 g/L (36-48)
Creatine: 95 mcmol/L (<100 mcmol/L)

Zinc: 14 mcmol/L (10-16)

Bilirubin: 31 mcmol/L (<26) (has always been elevated, doctors say Gilbert's syndrome. Any opinions?)
Aspartate aminotransferase (AST): 0.78 units/L (<0.76) (elevated, should I bee concerned?)
ALP: 1.2 (0.6-1.8)
S-gamma-GT: 0.22 (<1.4)
Orosomucoid: 0.48 (0.52-1.17)
Haptoglobin: 1 mg/dL (2.4-19) (low, cause for concern?)
Immunoglobulin A (IgA): 83 mg/dl (88-450) (low, cause for concern?)

Iron: 13 mcmol/L (9-34) (is this low?)
TIBC: 59 mcmol/L (47-80)
Iron saturation: 0.22 (0.15-0.60)
Ferritin: 83 mcg/L (30-200)
Lactate Dehydrogenase: 2.7 (<3.5)
Cortisol: 270 nmol/L (200-800) (really low, but I don't know how to raise morning cortisol)
Estradiol: <50 pmol/L (<50)
FSH: 4.4 U/L (0.7-11)
LH: 1.1 U/L (0.8-8.0)
Progesterone: <0.64 nmol/L (<2.0)
Testosterone: 9.2 nmol/L (>10)
SHBG: 37 nmol/L (10-57)

fT4: 13 pmol/L (9-22)
fT3: 3.2 pmol/L (2.5-5.6)
TPO antibodies: <0.5 kU/L (<5.6)
Tg antibodies: 2.2 kU/L (<4.1)
TSH-receptor antibodies: <1.0 IE/L (<1.0))

HbA1c: 30 mmol/mol (27-42)
25(OH)D: 146 nmol/L (25-105) (this was 48 nmol/L two months ago but D3 supplementation increased levels)

S-transglut antibodies: <8 AU/ml (<8)
Gliadine antibodies: <18 AU/L (<18)

S-PTH: 2.7 pmol/L (1.3-6.8)

S-IGF-1: 205 mcg/L (117-329)

Cobalamine: 686 pmol/L (150-800) (this was 355 pmol/L two months ago but mehtylcobalamine supplementation increased levels)
S-Methylmalonate: 0.08 mcmol/L (<0.28)

Follic acid: 44 nmol/L (7.0-40) (high, is this a problem?)
B9: 39 nmol/L (8-39)
Magnesium: 0.81 mmol/L (0.7-0.95)

Cholesterol: 4.0 mmol/L (2.9-6.1)
fP-Triglycerides: 0.44 mmol/L (0.45-2.6) (low, is this a problem?)
GH: 0.5 mIU/L (0-2.4)

Semen analysis:
Volume: 3.4 mL (1.5-6.0)
Concentration: 11 million/mL
Total count: 37 million (> 40)
Motility:
-rapid: 1%
-slow: 17%
-non-progressive: 2%
-immotility: 80%

Comments for Low testosterone levels, low body temp, cold intolerance, infertility

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No, you don't need malabsorption to have problems
by: Kerri Knox, RN- The Immune Queen!

Hi Anthony,

Your situation sounds fairly complicated, but with a half brother with Celiac, I'd say it's fairly certain that you are affected by gluten too. Unfortunately, it's simplistic to say that you need to have malabsorption to have problems from gluten. That is ONE way that gluten causes problems, but another is that it's 'inflammatory' and can be causing inflammation throughout your body. Another way is that the tiny amount of inflammation that is occurring in your digestive tract is causing Increased Intestinal Permeability which allows food proteins to leak through into your bloodstream and cause an immune response which can lead to all sorts of symptoms.

There may be other, more subtle ways that gluten affects people and causes symptoms. In fact, one symptom that leads to a diagnosis of Celiac disease is simply a skin condition called Dermatitis Herpetiformis. Even with NO other symptoms and no gastrointestinal problems and no other tests, you WILL get a diagnosis of Celiac Disease if you have Dermatitis Herpetiformis. However the reason for this skin condition is unknown, all we know is that it goes away when you get off of gluten.

Celiac also causes weight loss in some people, weight gain in others- if it were only a malabsorption issue, it should only lead to weight loss- but gluten problems seem to have many subtle reasons that they lead to problems that we may never know all of the reasons that it does cause these problems.


So, your first and best bet for getting better is to get off of gluten completely, 100% regardless of your antibody test results.

Then, I would also suggest that you also eliminate all processed foods, grains, dairy, etc. in order to get the most amount of nutrition and eliminate the maximum amount of food allergens as possible until you are better. My recommendation is essentially a 'paleolithic' or almost paleolithic diet. If you are unsure how to go about doing this, I suggest that you get the PS: Get the Real Food Summit and use the tools for a simple, clean diet that is easily manageable once you get to actually doing it consistently. Eat lots of fat. I suspect that you are not getting enough fat in your diet. Humans need LOTS of fat.

Also, selenium is one of the number one nutrient deficiencies that can lead to infertility. Try eating a few Brazil Nuts everyday for an easy way to get a bit more fat and to increase your selenium intake.

That's a good start, let me know if you have any questions.


Kerri Knox, RN



Low T and low LH
by: Ben

Hi Anthony,
Do you still use this email address? I would like to discuss with you as our situations are nearly identical. I tried to email you but it bounced

We're the same
by: Matt

Hi Anthony,

We are almost identical. I haven't looked at all your readings, but what scanned them. I wrote in haste last night, it was a bad day, but I share your awful, horrific, at least for me, symptoms.

I have severe cold sensitivities. What's strange is up until 3 years ago, I loved mountain climbing. I mean the alpine stuff. Now if I go outside without gloves, I have to rush back inside and run hot water over my hands until the reaction stops. And, a reaction it is, it can tail-spin into a full-blown, nerve dying circle of death that is very hard to get out of and very few on this planet can (and thank all that is good for that) can comprehend.

As I mentioned before, I do have a FDN MD on my team. A Functional Diagnostic Nutrition specialist, who is taking apart my bits and pieces to understand what's going on. The important bit in this is that I have someone who believes. She shes my Cortisol very low, and has done something about it, prescribing low doses of Hydrocortisol. It's worked. She's noted my very low body temperature (96F) and is working on it. Note my PCP and the specialist she sent me to, shrugged this stuff off.

I do note, and not having seen this site before, but now scanning it, it is very much in line with Functional medicine, THANK YOU, and I will be checking it out. It could be possible to use this site to gather the information to make your doctor a believer. It's all about the data, and showing them there is something to be done. Doctors want to believe they can do something - they also like to believe it was their idea.

I do also have the Very low Testosterone levels, which she is doing something about. I can't walk to my mailbox without getting exhausted. It's more than exhaustion, we are deep to our core Fatigued. She is doing something about it now. My numbers were low but in line when this first started, but over time with the Opiate use and just collapse of my body systems (I'm missing the word) it's no wonder my body stopped producing this.

The FDN doctor can talk the talk so well, and with the OATS test, for instant, with my genetics in hand and other tests, just rip me apart and describe down to my cell and mitochondria how things are so bad, and being on the other side, I believe her. But, I think you can, if you still have the mind for it, find it here.

The other thing I mentioned was the heavy metal poisoning. Their is a big fight going on right now in the US, with Chuck and Gena Norris maybe unfortunately leading the way, with this GBCA (Gadolinium Based Contrast Agent). There is a forum out there you can find that also is fighting for us. I was poisoned way back in 1996 and it was still showing up at 6x the baseline the last time I was tested in 2014. It shouldn't be there at all. Who knows the damage this has done, but that's the fight. Europe has band the particular stuff I was injected with. If you were injected with a contrast agent, I'd urge you to get a 24 hour unprovoked heavy metal's test, one that will detect Gadolinium. You can go through a process to rid yourself of the toxin, but I fear it's too late for me.

I wish you the best, and given your age, I really truly hope you can find a doctor who understands what they are learning, such as what they provide here on this site.

Kind Regards,

Matt


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