Looking for dosage instructions for Vitamin B12 Deficiency

by Jenn
(Hershey, PA)

I have self diagnosed myself with a vitamin B12 deficiency as my family doctor seems rather uneducated in this particular area. I do have the 1298 MTHFR genetic mutation, that I've read can cause a deficiency. I am always fatigued, sleep poorly, have difficulty concentrating, mild depression and anxiety, and have been diagnosed with regional myofascial pain syndrome, which I interpret as a diagnosis that says "I realize you have chronic neck/shoulder/upper back pain, but I have no idea why."

I started taking Jarrow Formulas Methyl B12 5000 mcg lozenges about 5 weeks ago. I haven't really noticed a difference over all. I may have felt better on days that I've taken 2 at the same time. I've read that the sublingual supplements are better absorbed. So, my questions are:

1. Should I try a different brand with a sublingual version?

2. Would a higher dose once a day be as beneficial as a 5000 mcg dose twice a day?

3. Are they better taken on an empty stomach or with meals?

4. Why are they in mcg dosages as opposed to mg in doses greater than 1 mg?

Your advice is greatly appreciated!


Comments for Looking for dosage instructions for Vitamin B12 Deficiency

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by: Kerri Knox, Registered Nurse

Hi Jenn,

So first of all, if you have Jarrow lozenges, they are almost certainly made to be put under the tongue, so just use them that way or let them dissolve in your mouth. Here's my page on dosage for B12:

Vitamin B12 Deficiency Treatment.

The AVERAGE woman WITHOUT B12 deficiency felt better on 10,000 mcg per day. Maybe you just need more. Or maybe it's not B12 deficiency or maybe not JUST B12 deficiency. Everyone wants it to be the ONE thing that is a 'silver bullet' that will fix all of their problems. But in reality, things do not work that way. If you have one nutrient deficiency, how did you GET that deficiency? Generally, nutrient deficiencies don't come 'isolated' by themselves, but together with multiple deficiencies.

For instance, have you checked your vitamin d level? Have you considered Gluten Sensitivity? Have you been checked for the H Pylori Bacteria? THere are really dozens of things that could be your problem that your doctor has simply not checked for.

So, as you've figured out, you need to be your own doctor and try out multiple things to try to get better.

Kerri Knox, RN

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