High B12 Levels in the Blood

by Becky

Recent lab work showed an elevated B12 of 512. This is in a 60 year old male patient. Should we be concerned?

Thank you,


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by: Kerri Knox, RN

Hi Becky,

That would depend entirely upon whether the individual is taking Vitamin B12 or not. If they are taking Vitamin B12, then it's meaningless and you should stop doing Vitamin B12 levels on someone who is taking B12 as it will virtually always be high. So, it's worthless and meaningless to do Vitamin B12 levels when they are taking Vitamin B12.

If they are NOT taking Vitamin B12, then a high level is almost certainly indicative of a MTHFR Gene Mutation. They should be tested for the gene, and treated appropriately.

HOWEVER, your question is strange because a level of 512 is completely normal. I'm not sure what you are concerned about. It's almost smack dab in the middle of the normal range. Maybe you are not using picograms per milliliter (pg/mL)?

If not, then what is the scale you are using, because 512 pg/ml is completely normal.

Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
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