Can quick-dissolve pills be crushed?

by Katja
(Victoria, BC)

My questions is about quick-dissolving pills. My husband had tonsil cancer last year,and now takes all nutrition, liquids, and medications via a G-tube. Are the quick-dissoving (sublingual) pills as effective when crushed, mixed with water, and injected directly into the stomach? Or do the stomach acids somehow denature the vitamins (both B12 and D3) which should normally dissolve on or under the tongue?

(My husband is very fatigued, with probable macrocytic anemia (RBC 3.56, MCV 101 (Canadian numbers)), but our family doc right away (probably because his last B12 test was in range) jumped to my husband having a slow leak of blood, or that his red blood cells are being destroyed in the blood. I found your site, and started him on 5 mg of B12 last night, and overnight I started wondering about stomach acids etc.).

Thank you very much for your time.



Comments for Can quick-dissolve pills be crushed?

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No Problems
by: Kerri Knox, The Immune System Queen

Hi Katja,

No, stomach acids don't destroy the B12. The only issue is whether he can absorb the B12 or not. The sublingual tabs were developed because many people taking them have a disorder called pernicious anemia where they lack a substance called 'intrinsic factor' in their stomach that is required to absorb B12. Unless your husband has 'frank' B12 deficiency, which he doesn't, then it's unlikely that he has this problem, so giving it to him in his stomach is just fine.

Since he's so profoundly ill, you may want to even consider giving him a higher dose. If you read my page on Vitamin B12 Deficiency Treatment, you'll see that studies were done giving people even as high a dose as 60 mg (60,000 mcg) per day without problems, and with some profound benefits.

Kerri Knox, RN

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